Table 2. Immunohistochemistry analysis and correlations with pCR for patients treated with anthracyclines.
| Parameter | Variables | % | %pCR | %non-pCR | P-values | Odds ratio |
|---|---|---|---|---|---|---|
| ER status | Positive | 51.6 | 6.4 | 93.6 | 0.001 | 0.132 (0.35–0.496) |
| Negative | 48.4 | 34.1 | 65.9 | |||
| PR status | Positive | 36.3 | 12.1 | 87.9 | 0.116 | 2.636 (0.765–9.080) |
| Negative | 49.4 | 26.7 | 73.3 | |||
| Missing | 14.3 | NA | NA | |||
| HER2 Status | Positive | 29.7 | 14.8 | 85.2 | 0.354 | 0.562 (0.164–1.923) |
| Negative | 60.4 | 23.6 | 76.4 | |||
| Missing | 9.9 | NA | NA | |||
| Topo2α status | High | 51.6 | 28.9 | 71.1 | 0.031 | 3.331 (1.076–10.315) |
| Low | 48.4 | 13.9 | 86.1 | |||
| EGFR status | High | 63.5 | 12.5 | 87.5 | 0.005 | 0.186 (0.053–0.647) |
| Low | 36.5 | 43.5 | 56.5 | |||
| p53 status | High | 39.7 | 36 | 64 | 0.015 | 4.781 (1.278–17.884) |
| Low | 60.3 | 10.5 | 89.5 | |||
| Ki67 status | High | 45.3 | 25 | 75 | 0.71 | 1.286 (0.390–4.238) |
| Low | 54.7 | 20.6 | 79.4 | |||
| Basal phenotype status | Positive | 52.7 | 14.9 | 85.1 | 0.26 | 0.542 (0.185-1.587) |
| Negative | 47.3 | 24.4 | 75.6 |
Abbreviation: not applicable. The columns for % pCR and % non-pCR show the response in each category of immunohistochemical variable (positive/negative; high/low). The Pearson's χ2-significance is presented in the P-value column. The Odds ratios with 95% confidence intervals are shown in brackets.