Table 1. Patient demographics of the colon cancer series used for gene selection, algorithm training and independent validation.
Training series | Independent validation series | |
---|---|---|
NCBI GEO ID | GSE17538 | GSE14333 |
Contributing institutes | Vanderbilt Medical Center (Nashville, TN) & H. Lee Moffit Cancer Center (Tampa, FL, USA) | The Peter MacCallum Cancer Centre, Westmead Hospital, & Royal Melbourne Hospital (Australia) |
Number of samples | 232 | 60 |
Age (years), mean±s.d. | 64±13.4 | 68±13.7 |
Stage 1, n (%) | 28 (12%) | — |
Stage 2, n (%) | 72 (31%) | 33 (55%) |
Stage 3, n (%) | 76 (33%) | 27 (45%) |
Stage 4, n (%) | 56 (24%) | — |
Gender: female, n (%) | 110 (47%) | 28 (47%) |
Gender: male, n (%) | 122 (53%) | 32 (53%) |
Adjuvant chemotherapy | — | 22 (37%) |
Adjuvant radiotherapy | — | 1 (2%) |
Median follow-up/survival (months), (range) | 30 (0–210) | 37 (2–85) |
No. recurrences, n (%) | 55 (23%) | 16 (17%) |
No. deaths, n (%) | 93 (40%) | NA |
Abbreviation: NA=not applicable.