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. 2010 Nov 9;103(12):1815–1821. doi: 10.1038/sj.bjc.6605979

Table 3. Anticancer drugs most often prescribed to patients in the study.

INN No. of prescriptions Percent of prescription (%) Need for dosage adjustment in RI Potential nephrotoxicity
Fluorouracil 248 13.6 No No
Zoledronate 220 12.1 Yes Yes
Docetaxel 114 6.2 Yes No
Cyclophosphamide 101 5.5 Yes No
Epirubicin 94 5.2 No SC
Trastuzumab 92 5.0 ND SC
Gemcitabine 90 4.9 No Yes
Cisplatin 89 4.9 Yes Yes
Carboplatin 70 3.8 Yes Yes
Paclitaxel 63 3.5 No SC
Oxaliplatin 61 3.3 No Yes
Irinotecan 53 2.9 No Yes
Doxorubicin 52 2.8 No SC
Capecitabin 47 2.6 Yes No
Letrozole 42 2.3 No No
Tamoxifen 41 2.2 No SC
Ibandronate 35 1.9 Yes No
Vinorelbine 32 1.8 Yes No
Exemestane 30 1.6 No No
Temozolomide 22 1.2 ND No
Cetuximab 18 1.0 No Yes
         
Other 238 12.9 Yes: 28.2% Yes: 100 prescriptions
      ND: 31.5% ND: 18 prescriptions
      No: 40.3% No: 100 prescriptions
         
Total 1852 100 Yes: 41.8% Yes: 1043 prescriptions
      ND: 10.2% ND: 18 prescriptions
      No: 47.9% No: 791 prescriptions

Abbreviations: INN=international non-proprietary name; ND=no data available in the literature for use in patient with RI or for nephrotoxicity; RI=renal insufficiency; SC=sparse cases.

Other: anticancer drugs that were prescribed in <1% of patients in the study (decreasing number of prescriptions): bevacizumab, gosereline, etoposide, fulvestrant, methotrexate, topotecan, anastrozole, dacarbazine, vinblastine, erlotinib, vinflunine, mitoxantrone, bicalutamide, mitomycine, megestrole, pamidronate, imatinib, ifosfamide, vaccine, bleomycin, lomustin, estramustin, fotemustin, gefitinib, leuproreline, octreotide, hydroxycarbamide, pemetrexed, triptoreline, sunitinib, panitumumab, thyrixine, cyproterone, carmustine, rituximab, streptozocine, matuzumab, sorafenib, lanreotide, ipilimumab.