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. 2010 Nov 9;103(12):1822–1830. doi: 10.1038/sj.bjc.6605980

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Copyright © 2010 Cancer Research UK

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Fibroblast growth factor 2-targeted gene delivery system significantly increases transgene expression in tumour cells. Representative pictures after 1 and 3 days after adenoviral infection at an MOI of 5 (A) and 10 (B). Relative intensity of GFP expression at an MOI of 5 (C) and 10 (D). The benefit of FGF2-targeted transgene was greater at an MOI of 5 and sufficient gene transduction looks promising even after a lower titre adenoviral administration. ^*P<0.01.