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. 2010 Nov 9;103(12):1822–1830. doi: 10.1038/sj.bjc.6605980

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Copyright © 2010 Cancer Research UK

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Downregulation of NF-κB expression after FGF2-targeted Ad-NBS1 gene transfer. Downregulation of NF-κB expression (P<0.05) is seen after infection with FGF2-targeted Ad-NBS1 relative to non-infected controls, Ad-GFP or Ad-NBS1. This result indicates that FGF2-targeted Ad-NBS1 downregulates NF-κB activity, and which may lead to antiangiogenesis effects. ^*P<0.01 when compared with FGF2-Ad-NBS1.