Figure 4.
In vivo aptamer and antidote activity. (a–c) ACT clotting times of blood from swine treated with the cholesterol-modified FIXa aptamer 9.3t (Ch-9.3t) in pigs (n = 5) alone (a) or with the addition of protamine (b) or CDP (c). The data are plotted as the means ± s.e.m. for duplicate measurements from each pig.