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. 2010 Dec 22;5(12):e14402. doi: 10.1371/journal.pone.0014402

Figure 1. Ppt1 LOF mutants exhibit abnormal complement of EVE+ neural precursors and neurons.

Figure 1

(A) In wild type, EVE is expressed in GMC4-2.a, the neural precursor that give rise to RP2 motoneuron and its sib (arrow); and in a cluster of GMCs that give rise to the aCC, pCC, CQ neurons (arrowhead). (B–E) In Ppt1 mutants, many hemisegments exhibit a variety of phenotype including the loss of GMC4.2a (arrow in B and E), extra RP2/sib neurons (arrowhead in D), disorganized EVE+ clusters (C), and extra aCC/pCC cells (arrowhead in E). In all panels, embryos are at S11–12 of development; anterior, up; caret, midline.