Table 5. Quantitation of Ppt1 axon defects in the embryonic CNS and PNS.
| phenotype | Wild type | Ppt1A179T | Ppt1446-20 | Ppt15499RNAi×elav-gal4 | Ppt125952TRiP RNAi×elav-gal4 | Ppt15499RNAi×UAS tauLacZ CQ2-gal4 | Ppt15499RNAi×UAS tauLacZ RN2-gal4 |
| PNS | |||||||
| Irregular spacing of lch5 neuron clusters | 0 | 6 | 6 | n/d | n/d | n/d | n/d |
| Missing lch5 neurons | 0 | 4 | 6 | n/d | n/d | n/d | n/d |
| Malformed lch5 neurons | 0 | 13 | 13 | n/d | n/d | n/d | n/d |
| CNS | |||||||
| slightly irregular and/or wavy longitudinal tracts | 0 | 31 | 21 | 40 | 9 | 25 | 7 |
| Discontinuous, frayed longitudinal tracts | 0 | 8 | 11 | 35 | 33 | 35 | 99 |
| Irregular, missing or fused commissures | 0 | 16 | 17 | 6 | 14 | 7 | 10 |
| Total number of embryos scored | 27 | 69 | 58 | 81 | 42 | 67 | 106 |
-number of embryos of each genotype displaying various fasII and 22C10 defects; many embryos exhibit combination of phenotypes.
n/d: not determined.