Table 1. Motifs identified in Passenger Sub-domains D0, D4–D10 and D12–D14.

Domain	N-terminal Motif	Central Motif	C-terminal Motif
D0	A(ND)		(LIV)
D4	FPXXXF	YX(WF)XSS	GX(IV)T(FIL)
D5	W(V/I/F)	G(ST)L(WYF)(GS)EWG(ND)(LM)XXY	W
D6	CPXXXXGXXXXC	EVRDG	LVSTXXGTFXXXXDXGXYG
D7	DGVVMDL	LYDXXDK	P
D8			GDQG(FY)GLKV
D9			SYXLX6P
D10	VXXLXPXXIW		CXKXXXG(ST)YX7YX6YX7WXG
D12		VTVXFPDG(ST)XKT
D13	See Fig S12
D14	See Fig S13

For each motif: boldface, fully-conserved residues.

Conserved motifs identified in passenger subdomains D0, D4–D10 and D12–D14.