Table 1. Patient and tumor characteristics stratified by nuclear RB1CC1 expression.
| Feature | Number | Nuclear RB1CC1 | p-Value | |||
| negative | (%) | positive | (%) | |||
| Menopause | 0.1204 | |||||
| Pre- | 142 | 37 | (37) | 105 | (47) | |
| Post- | 182 | 62 | (62) | 120 | (53) | |
| anti-Estrogen therapy | 0.0540 | |||||
| none | 85 | 33 | (33) | 52 | (23) | |
| performed | 239 | 66 | (67) | 173 | (77) | |
| Chemotherapy | <0.0001 | |||||
| none | 179 | 33 | (33) | 146 | (65) | |
| performed | 145 | 66 | (67) | 79 | (35) | |
| Radiation | 0.1248 | |||||
| none | 108 | 27 | (27) | 81 | (36) | |
| performed | 216 | 72 | (73) | 144 | (64) | |
| T grade: tumor size | 0.0805 | |||||
| ≤T1 | 138 | 35 | (35) | 103 | (46) | |
| T2≤ | 186 | 64 | (65) | 122 | (54) | |
| Nodes | 0.0567 | |||||
| negative | 210 | 56 | (58) | 154 | (69) | |
| positive | 111 | 41 | (43) | 70 | (31) | |
| Stage: TNM class | 0.2605 | |||||
| ≤IIA | 228 | 64 | (67) | 164 | (73) | |
| IIB≤ | 93 | 32 | (33) | 61 | (27) | |
| ER | 0.0689 | |||||
| positive | 188 | 50 | (51) | 138 | (61) | |
| negative | 136 | 49 | (49) | 87 | (39) | |
| PR | 0.0003 | |||||
| positive | 170 | 37 | (37) | 133 | (59) | |
| negative | 154 | 62 | (63) | 92 | (41) | |
| HER2 | 0.1553 | |||||
| negative | 290 | 85 | (86) | 205 | (91) | |
| positive | 34 | 14 | (14) | 20 | (9) | |
| Triple Negative | 0.0003 | |||||
| others | 237 | 59 | (60) | 178 | (79) | |
| triple negative | 87 | 40 | (40) | 47 | (21) | |
| p53 | 0.3200 | |||||
| normal | 244 | 71 | (72) | 173 | (77) | |
| abnormal | 80 | 28 | (28) | 52 | (23) | |
| RB1 | 0.0833 | |||||
| positive | 308 | 91 | (92) | 217 | (96) | |
| negative | 16 | 8 | (8) | 8 | (4) | |
| RB1CC1 | ------ | |||||
| positive | 225 | 0 | (0) | 225 | (100) | |
| negative | 99 | 99 | (100) | 0 | (0) | |
| RB1CC1/RB1/p53 | ------ | |||||
| normal | 169 | 0 | (0) | 169 | (75) | |
| abnormal | 155 | 99 | (100) | 56 | (25) | |
Chi-square and Fisher's exact tests was used to evaluate the relationships between clinical parameters and nuclear RB1CC1 expression. p-value <0.05, statistically significant.