Table 2. Relative hazards of risk factors for breast cancer-specific death.
| Features | Number | (%) | hazard ratio | (95% CI) | p-Value |
| Menopause | |||||
| Pre- | 142 | (44) | 1.000 | ||
| Post- | 181 | (56) | 0.871 | (0.479–1.584) | 0.6506 |
| anti-Estrogen therapy | |||||
| none | 85 | (26) | 1.000 | ||
| performed | 238 | (74) | 0.920 | (0.472–1.792) | 0.8063 |
| Chemotherapy | |||||
| none | 179 | (55) | 1.000 | ||
| performed | 144 | (45) | 5.000 | (2.398–10.418) | <0.0001 |
| Radiation | |||||
| none | 108 | (33) | 1.000 | ||
| performed | 215 | (67) | 0.571 | (0.313–1.044) | 0.0685 |
| T grade: tumor size | |||||
| ≤T1 | 138 | (43) | 1.000 | ||
| T2≤ | 185 | (57) | 4.167 | (1.855–9.346) | 0.0005 |
| Nodes | |||||
| negative | 210 | (66) | 1.000 | ||
| positive | 110 | (34) | 4.082 | (1.980–6.993) | <0.0001 |
| Stage: TNM class | |||||
| ≤IIA | 228 | (71) | 1.000 | ||
| IIB≤ | 92 | (29) | 3.704 | (2.008–6.803) | <0.0001 |
| ER | |||||
| positive | 187 | (58) | 1.000 | ||
| negative | 136 | (42) | 3.206 | (1.694–6.070) | 0.0003 |
| PR | |||||
| positive | 170 | (53) | 1.000 | ||
| negative | 153 | (47) | 6.562 | (2.919–14.751) | <0.0001 |
| HER2 | |||||
| negative | 290 | (90) | 1.000 | ||
| positive | 33 | (10) | 2.151 | (0.997–4.630) | 0.0507 |
| Triple Negative | |||||
| others | 236 | (73) | 1.000 | ||
| triple negative | 87 | (27) | 4.149 | (2.271–7.579) | <0.0001 |
| p53 | |||||
| normal | 243 | (75) | 1.000 | ||
| abnormal | 80 | (25) | 1.737 | (0.928–3.254) | 0.0843 |
| RB1 | |||||
| positive | 307 | (95) | 1.000 | ||
| negative | 16 | (5) | 5.325 | (2.353–12.049) | <0.0001 |
| RB1CC1 | |||||
| positive | 224 | (69) | 1.000 | ||
| negative | 99 | (31) | 3.373 | (1.840–6.185) | <0.0001 |
| RB1CC1/RB1/p53 | |||||
| normal | 168 | (52) | 1.000 | ||
| abnormal | 155 | (48) | 7.385 | (3.116–6.185) | <0.0001 |
The Cox proportional hazard regression model was used to evaluate the effects of clinico- pathological parameters on disease-specific-survival (DSS) with 95% confidence interval (95% CI). p-value <0.05, statistically significant. DSS intervals were used as the indicator for the relative-hazards.