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. Author manuscript; available in PMC: 2010 Dec 23.
Published in final edited form as: Science. 2010 Apr 8;328(5981):1036–1040. doi: 10.1126/science.1186176

Figure 1.

Figure 1

CEBPA binding in vivo in livers isolated from five vertebrate species cross-mapped to the human PCK1 gene locus. A rare ultraconserved binding event is shown surrounded by species-specific and partially-shared binding events. On the left is the evolutionary tree of the five study species (Hsap=Homo sapiens; Mmus=Mus musculus; Cfam=Canus familiaris; Mdom=Monodelphis domesticus; Ggal=Gallus gallus), with their approximate evolutionary distance in millions of years (MY). The bottom track shows evolutionary conservation measured across 44 vertebrate species, and darker shading represents slower evolution.