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. 2010 Sep 27;588(Pt 22):4475–4488. doi: 10.1113/jphysiol.2010.198366

Figure 6. STDP protocols at non-MF inputs.

Figure 6

A and B, STDP protocols that induced plasticity at MF inputs to CA3 neurons failed in inducing plasticity at s. radiatum stimulated non-MF inputs. Averaged values for normalized EPSP amplitude, input resistance and membrane potential are plotted against time for recordings with three APs paired with an EPSP at positive timing (A, Δt = +10 ms, n = 6) or with single AP pairing at negative timing (B, Δt = −30 ms, n = 5), as shown by the respective schematic drawing in the grey insets. The bar insets illustrate changes of EPSP amplitudes by the group II mGluR agonist; EPSPs were set to 100% before washing in the group II mGluR agonist.