Table 4.
Literature comparison of metal ion levels in patients with MOM-THA
| Study | Analysis | Implant | Type of study | Time | Samples and ion values |
|---|---|---|---|---|---|
| Back et al. [3] | ICP-MS AAS | BHR | Prospective | Preoperative, 3, 6, 9 months, 1, and 2 years |
Serum, mean values, nmol/L, 2 years Co: 31.8; Cr: 67.9 |
| Clarke et al. [5] | ICP-MS | BHR Cormet 2000 Ultima |
Retrospective | 7–56 months (median, 16) | Serum, median values, nmol/L BHR/Cormet, 2000 Co: 38, Cr: 53 Ultima, Co: 22, Cr: 19 |
| Daniel et al. [6] | ICP-MS | BHR | Prospective | Preoperative, 5 days, 2, 6 months, 1, 2, 4, 6 years |
Whole blood, mean values, ng/mL 1 year, Co: 1.26; Cr: 2.41 4 years, Co: 1.21; Cr: 1.12 6 years, Co: 1.17; Cr 1.11 |
| Garbuz et al. [11] | ICP-MS | Durom resurfacing Metasul |
Prospective randomized | Preoperative, 2 months, 1, and 2 years |
Serum, median values, ng/mL, 2 years Metasul, Co: 5.8; Cr: 2.9 Durom resurf., Co: 0.54; Cr: 0.8 |
| Hart et al. [17] | ICP-MS | MOM resurfacing (type not specified) | Prospective | Not specified | Whole blood, median values, ng/mL Co: 4.5; Cr: 3.0 |
| Moroni et al. [27] | AAS | BHR, Metasul (monolateral and bilateral) | Retrospective | 2 years | Serum, mean values, ng/mL BHR, Co: 1.4; Cr: 2.3 Metasul, Co: 1.7; Cr: 1.3 |
| Savarino et al. [29] | AAS | Metasul | Retrospective | 14-38 months (median, 25) | Serum, mean values, ng/mL Co: 1.3; Cr: 1.7 |
| Skipor et al. [34] | AAS | Resurfacing Conserve® Plus | Prospective | Preoperative, 3, 6, 12 months |
Serum, mean values, ng/mL, 12 months Co: 1.1; Cr: 1.8 |
| Vendittoli et al. [38] | ICP-MS | THR and Durom resurfacing system | Prospective randomized clinical trial | Preoperative, 3, 6, 12, 24 months |
Mean values, ng/mL, 24 months Whole blood, Co: 0.6; Cr: 1.4 Serum, Co: 1.4; Cr: 1.4 Erythrocytes, Co: 0.8; Cr: 1.0 |
| Witzleb et al. [39] | AAS | BHR and Metasul | Retrospective | 3, 12, 24 months | Serum, median values, ng/mL, 24 months BHR, Co: 4.3; Cr: 5.1 Metasul, Co: 1.7; Cr: 1.22 |
| Current study | AAS | BHR, Metasul (monolateral) | Retrospective | 2 and 5 years | Serum, mean values, ng/mL 2 years Metasul, Co: 1.3; Cr:1.8, BHR Co: 1.2; Cr: 2.2 5 years Metasul, Co: 1.4; Cr:1.9, BHR Co: 1.1; Cr: 2.3 |