Fig. 1.

The course of a patient who received antilymphocyte globulin (ALG) before and for the first 4 months after renal homotransplantation. The donor was an older brother. The Terasaki match was grade A. There was no early rejection. Prednisone therapy was started 40 days postoperatively because of the high rises in the serologic titers which warned against a possible anaphylactic reaction. Note the insidious onset of late rejection after cessation of globulin therapy. This was treated by increasing the maintenance dose of steroids. This delayed complication occurred in only 2 of the original 20 patients.