Table 1.
Code | Sequence a | Comment |
---|---|---|
2 | Cyclo(1,11) H-E1S2I3Y4D5P6G7D8D9I10K11-OH | Cyclized by side chain of E1 and K11 |
3 | Cyclo(1,10) E1I2Y3D4P5G6D7D8I9K10 | Main chain cyclization |
4 | Cyclo(1,10) H-E1I2Y3D4P5G6D7D8I9K10-OH | Cyclized by side chain of E1 and K10 |
Control | KGKTDAISVKAI-NH2 | Reversal of sequence and replacement of Y81 and Y86 by Ala |
FITC-4 | FITC-Cyclo(1,10) H-E1I2Y3D4P5G6D7D8I9K10-OH | Fluoresceineisothiocyanate attachment at N-terminal via amino hexanoic acid (Ahx) |