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Global hypomethylation stratified by Lauren classification and tumor localization among cases
| No. | Mean Alu methylation (SD) | No. | Mean LINE-1 methylation (SD) | |
|---|---|---|---|---|
| Lauren classification | ||||
| Intestinal | 203 | 25.0 (1.4) | 202 | 80.1 (3.7) |
| Diffuse | 50 | 24.9 (1.4) | 50 | 79.7 (3.8) |
| Indeterminate | 32 | 25.0 (1.5) | 31 | 80.6 (2.9) |
| p-value | 0.82 | 0.54 | ||
| Tumor localization | ||||
| Cardia only | 35 | 24.7 (1.4) | 35 | 79.4 (4.1) |
| Distal stomach | 221 | 25.0 (1.4) | 219 | 80.1 (3.6) |
| Combined cardia/distal | 35 | 25.1 (1.3) | 35 | 80.7 (2.9) |
| p-value | 0.34 | 0.33 | ||
