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. Author manuscript; available in PMC: 2010 Dec 23.
Published in final edited form as: Analyst. 2009 Dec 22;135(3):441–451. doi: 10.1039/b907735a

Figure 4.

Figure 4

Fabrication, prototype and use of the modular ion channel chip. (a) Assembly of the chip. The analyte can be added from the sample cell on the back of either compartment and delivered to the sensor element through agarose layered between the sample cell and the membrane. (b) A device prototype. (c) Signature blocks by the second messenger IP3 (500 nM) on the chip in a simulated intracellular conditions: 150 mM KCl, 2 mM ATP, 2.3 mM MgCl2, 10 mM Tris, 0.3 mM ATP, pH 7.4. This figure has been modified from reference71.