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. Author manuscript; available in PMC: 2010 Dec 23.
Published in final edited form as: Analyst. 2009 Dec 22;135(3):441–451. doi: 10.1039/b907735a

Figure 5.

Figure 5

Incorporation of the protein pore in the lipid bilayer suspended over a glass nanopore (GNP) membrane81. The GNP is a single conical-shaped nanopore embedded in a 50 μm glass membrane. The fabrication of GNP membrane was described in the reference82. The interior and exterior surfaces of the GNP are coated with 3-cyanopropyldimethylchlorosilane to form a hydrophobic surface, which allows the formation of lipid monolayer on it. Lipid monolayers on the interior and exterior surfaces of the GNP will merge to form an exceptionally stable bilayer across the GNP.