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. 2010 Jan 18;11(Suppl 1):S10. doi: 10.1186/1471-2105-11-S1-S10

Table 4.

Average performance of 10-fold cross validation.

Kinase New method Kinase New method Kinase New method
ACC P R ACC P R ACC P R
CDK_group 0.92 0.60 0.88 MAPK3 0.93 0.61 0.73 CDK1 0.94 0.63 0.90
GSK-3_group 0.88 0.32 0.17 MAPK1 0.94 0.66 0.80 CDK2 0.94 0.65 0.87
PLK1 0.90 0.00 0.00 MAPK8 0.91 0.53 0.83 CK2 alpha 0.95 0.76 0.66
GRK_group 0.91 0.15 0.07 Lck 0.92 0.75 0.20 Lyn 0.92 0.67 0.23
EGFR 0.92 0.69 0.42 PKC_group 0.92 0.76 0.30 RSK_group 0.96 0.80 0.85
MAPK14 0.93 0.67 0.60 Src 0.92 0.69 0.27 DNA-PK 0.88 0.40 0.35
InsR 0.93 0.62 0.45 IGF1R 0.95 0.76 0.70 Aurora 0.92 0.58 0.26
CK2_group 0.94 0.71 0.58 ATM 0.96 0.87 0.70 Met 0.96 0.80 0.85
AMPK_group 0.94 0.60 0.27 Abl 0.93 0.77 0.30 PHK_group 0.90 0.10 0.05
MAPKAPK2 0.92 0.63 0.33 PDK-1 0.96 0.86 0.67 GRK-2 0.94 0.30 0.15
CK1_group 0.90 0.20 0.10 PKA alpha 0.95 0.78 0.57 ROCK_group 0.94 0.70 0.35
PKA_group 0.95 0.81 0.59 IKK_group 0.91 0.43 0.20 FGFR1 0.89 0.10 0.05
PKC alpha 0.92 0.69 0.28 CaM-KIIalpha 0.94 0.65 0.37 PDGFR 0.94 0.70 0.45
Syk 0.94 0.86 0.54 GSK-3beta 0.90 0.32 0.12 CK1 0.93 0.55 0.23
Fyn 0.90 0.25 0.13 CaM-KII_group 0.92 0.62 0.20 CDK5 0.97 0.87 0.75
MAPK_group 0.92 0.64 0.54 PKB_group 0.94 0.93 0.41 PAK1 0.94 0.50 0.25

The mean accuracy, precision, and recall of the new method for 48 kinases are 0.93, 0.59, and 0.43, respectively.