Table 1.
Mean coefficient of variation and its standard deviation in MCF-7 cells treated with E2 and anti-estrogens.
| MCF-7 cells | EtOH | E2 | ICI | RU58 | OHT | RU39 |
|---|---|---|---|---|---|---|
|
CV (± SD) |
0,0248 (± 0,008) |
0,061 (± 0,013) |
0,0575 (± 0,019) |
0,0622 (± 0,019) |
0,0351 (± 0,009) |
0,0425 (± 0,013) |
Coefficients of variation of fluorescent intensities were measured after treatment with 10 nM E2 and anti-estrogens as described in Methods. The distribution of the intensity of the fluorescent signals was determined within nuclei excluding the nucleolus in MCF-7 cells (n = 15 - 20 cells).