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. 2010 Nov 30;11:152. doi: 10.1186/1471-2202-11-152

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Copyright ©2010 Lee et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Quantitative determination of mRNA levels in rat hippocampus obtained from rats that were administered antidepressants as determined by RT-PCR. Changes in the mRNA levels of DEGs identified in rat hippocampus from rats that had been treated with antidepressants were confirmed by real time PCR. Ten DEGs identified by microarray analysis were selected for confirmation. The dashed line indicates the control mRNA levels. All data were normalized by dividing the results by the amount of GAPDH expressed. Data are presented as mean ± S.E.M. (n = 4) *p < 0.05 and ** p < 0.01 compared to control.