Skip to main content
. 2010 Dec 15;10:683. doi: 10.1186/1471-2407-10-683

Table 1.

Patterns of endothelial VEGFR2 expression in tumor blood vessels in xenografted tumors and clinical cancer

Tumor Type # of Tumors % VEGFR2 Positive % VEGFR2 Negative
SW480 xenograft 4 60 ± 10.57a 40 ± 12.61c

Clinical colorectal carcinoma 36 60 ± 3.06a 40 ± 2.54c

WM239 xenograft 10 91.96 ± 3.01b 8.04 ± 0.41d

Clinical metastatic melanoma 14 93 ± 3.29b 7 ± 0.33d

Table I - VEGFR2 heterogeneity was assessed in human clinical specimens and xenografts of both colorectal carcinoma and metastatic malignant melanoma using dual immunofluorescence staining for VEGFR2 and CD31. The mean values for average percentage of VEGFR2 positive and VEGFR2 negative vessels were calculated along with SEM. Values with the same superscript (a-m) are significantly different from the same vessel class in different cancer types, but not from each other (p < 0.05).