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. 2010 Nov 30;11:585. doi: 10.1186/1471-2105-11-585

Table 1.

Main biological processes in response to IL-6

Source Mode Biological process
1 positive (external) stimulus, inflammatory response
negative (fructose) metabolic process
2 positive early cell cycle and division
negative metabolic process, apoptosis
3 positive late cell cycle and division
negative -
4 positive translation, coagulation
negative (protein) metabolic process

Summary of the main biological processes in hepatocytes regulated as response to IL-6. Mode indicates genes with significant positive (≥2) or negative (≤-2) contribution to the source. The main biological processes found for the corresponding group of genes are given in the last column.