Figure 6. The macrophage response to Mp in mouse lung is MyD88-dependent.
WT and MyD88−/− mice were inoculated with Mp, and (A) the survival of Mp in the lungs was determined at the indicated times. (*p<0.05) (B) Total leukocytes were recovered from collagenase-digested lungs, and cells were stained with anti-CD11c and anti-CD11b prior to analysis by flow cytometry. Three independent experiments showed similar results. Data shown are means ± SEM (n = 4 or 5). *p<0.05.