Table 5. TLR4 A1571T and TLR4 G1807A genotype association with inflammatory bowel disease in German shepherd dogs.

TLR4 A1571T SNP association with IBD
Model	Genotype	Control	Case	OR (95% CI)	P-value	AIC	BIC
Codominant	T/T	48 (80%)	38 (70.4%)	1.00	0.0093	154.4	162.6
	A/T	12 (20%)	10 (18.5%)	1.05 (0.41–2.70)
	A/A	0 (0%)	6 (11.1%)	NA (0.00-NA)
Dominant	T/T	48 (80%)	38 (70.4%)	1.00	0.23	160.3	165.8
	A/T-A/A	12 (20%)	16 (29.6%)	1.68 (0.71–3.98)
Recessive	T/T-A/T	60 (100%)	48 (88.9%)	1.00	0.0022	152.4	157.9
	A/A	0 (0%)	6 (11.1%)	NA (0.00-NA)
Overdominant	T/T-A/A	48 (80%)	44 (81.5%)	1.00	0.84	161.7	167.2
	A/T	12 (20%)	10 (18.5%)	0.91 (0.36–2.31)
Log-additive	---	---	---	1.99 (0.98–4.01)	0.047	157.8	163.2

Frequency and significance of the TLR4 A1571T and TLR4 G1807A single nucleotide polymorphism genotype in a case-control association study in German shepherd dogs (GSDs) with inflammatory bowel disease using a SNaPSHOT multiplex reaction (case = 55 unrelated GSDs, control = 61 GSDs) (OR-Odds ratio, AIC- Akaike information criteria, BIC-Bayesian information criteria).