Table 6. TLR5 G22A, TLR5 C100T and TLR5 T1844C genotype association with inflammatory bowel disease in German shepherd dogs.

TLR5 G22A SNP association with IBD
Model	Genotype	Control	Case	OR (95% CI)	P-value	AIC	BIC
Codominant	G/G	57(93.4%)	34(61.8%)	1.00	1e-04	147.9	156.2
	A/G	4 (6.6%)	20(36.4%)	8.38(2.64–26.59)
	A/A	0 (0%)	1 (1.8%)	NA (0.00-NA)
Dominant	G/G	57(93.4%)	34(61.8%)	1.00	<0.0001	146.3	151.8
	A/G-A/A	4 (6.6%)	21(38.2%)	8.80(2.79–27.81)
Recessive	G/G-A/G	61 (100%)	54(98.2%)	1.00	0.22	163	168.5
	A/A	0 (0%)	1 (1.8%)	NA (0.00-NA)
Overdominant	G/G-A/A	57(93.4%)	35(63.6%)	1.00	<0.0001	147.9	153.4
	A/G	4 (6.6%)	20(36.4%)	8.14 (2.57–25.80)
Log-additive	---	---	---	8.51 (2.71–26.70)	<0.0001	145.9	151.5

Frequency and significance of the TLR5 G22A, TLR5 C100T and TLR5 T1844C single nucleotide polymorphism genotype in a case-control association study in German shepherd dogs (GSDs) with inflammatory bowel disease using a SNaPSHOT multiplex reaction (case = 55 unrelated GSDs, control = 61 GSDs; 47 GSDs with non-inflammatory disease and 14 healthy GSDs) (OR-Odds ratio, AIC- Akaike information criteria, BIC-Bayesian information criteria).