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Characterization of the RWG imager. (a) The basal λr image (inset) and distribution of a biosensor having partial cell coverage. The λr values were binned for every 25 pm. (b) The kinetic responses to histamine at 3 pixels [A, B, and C in (a)]. The DMR amplitude is also indicated as P-DMR (positive-DMR). [(c) and (d)] The correlation between the histamine DMR amplitude and its corresponding basal λr value for fully and partially confluent cells, respectively.
