Table 2.

Target sites in ORFs and classes of IGRs

	Haploid, %	Diploid, %	in Vitro, %	MRC, %	Yeast genome, %
Genome
ORF	40.8*	45.4*	75.3*	69.8	70.6
IGR	59.2*	54.6*	24.7*	30.2	29.4
Breakdown of intergenic regions
Tandem	51.0	51.0	49.2	49.8	51.5
Convergent	11.1	10.12	15.3	17.08	15.5
Divergent	37.4	38.64	33.74	32.19	33.2

Number of Hermes target sites in ORFs and IGRs in in vivo haploid and diploid yeast datasets and the in vitro dataset is contrasted with a matched random control (MRC) as well as the ratios from the yeast genome. Also shown is the distribution of target sites in classes of intergenic regions: IGRs flanked by two 5′ gene boundaries (divergent), IGRs flanked by two 3′ gene boundaries (convergent), and other orientations (tandem).

*P < 0.001, Fisher's exact test.