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Complete liver regeneration with DDB1-expressing hepatocytes after induced DDB1 deletion. DDB1 staining on liver sections from (A) adult DDB1F/F;Mx1-Cre+/− mice 2, 4, or 8 wk after poly(I:C) injection or (B) mice 2 or 8 wk after the second poly(I:C) injection. (C) Ki67 IHC staining and (D) TUNEL analysis on liver sections from mice 4 or 8 wk after poly(I:C) injection. Arrows indicate TUNEL-positive cells.
