Table 3.

Age- and Multivariate-Adjusted Hazard Ratios for Specific Alcoholic Beverage Use and Incident Hearing Loss

Beverage and Frequency of Use	Cases	Person-years	Age-adjusted Hazard Ratio (95% CI)	Multivariate-adjusted Hazard Ratio* (95% CI)
Beer
<1/month	1629	175029	1.00 (ref)	1.00 (ref)
1/mo–1/wk	1089	118953	1.04 (0.96–1.12)	1.01 (0.92–1.10)
2–4/wk	386	47893	0.98 (0.88–1.10)	0.94 (0.83–1.06)
5/wk–1/d	204	26935	0.95 (0.82–1.10)	0.92 (0.79–1.08)
>1/d	84	10995	0.99 (0.80–1.23)	0.98 (0.78–1.23)
Red Wine
<1/month	1741	197492	1.00 (ref)	1.00 (ref)
1/mo–1/wk	1018	119240	0.98 (0.91–1.06)	0.96 (0.87–1.06)
2–4/wk	408	39503	1.10 (0.98–1.22)	1.02 (0.90–1.16)
5/wk–1/d	178	19048	0.94 (0.80–1.09)	0.93 (0.78–1.10)
>1/d	45	4960	0.91 (0.67–1.22)	0.89 (0.66–1.21)
White Wine
<1/month	1455	166156	1.00 (ref)	1.00 (ref)
1/mo–1/wk	1301	148984	1.04 (0.96–1.12)	1.04 (0.95–1.14)
2–4/wk	438	43222	1.19 (1.07–1.32)	1.19 (1.05–1.35)
5/wk–1/d	146	16803	1.07 (0.79–1.45)	1.01 (0.84–1.21)
>1/d	43	4553	1.02 (0.80–1.81)	1.07 (0.78–1.46)
Wine, combined
<1/month	1225	140550	1.00 (ref)	1.00 (ref)
1/mo–1/wk	1251	145216	1.02 (0.94–1.10)	1.01 (0.93–1.10)
2–4/wk	584	58478	1.12 (1.02–1.24)	1.14 (1.02–1.27)
5/wk–1/d	280	30357	0.98 (0.86–1.12)	0.99 (0.86–1.14)
>1/d	83	9079	0.97 (0.78–1.22)	0.97 (0.77–1.22)
Liquor
<1/month	1658	196097	1.00 (ref)	1.00
1/mo–1/wk	804	92300	1.07 (0.98–1.17)	1.06 (0.97–1.17)
2–4/wk	388	42152	1.07 (0.95–1.19)	1.02 (0.91–1.15)
5/wk–1/d	356	32819	1.14 (1.02–1.28)	1.09 (0.96–1.23)
>1/d	205	18063	1.15 (0.99–1.33)	1.09 (0.93–1.27)

^*Adjusted for age, body mass index, physical activity, folate, vitamin B12, smoking, hypertension, diabetes, profession, race, hypercholesterolemia, cardiovascular disease, gout, furosemide use, aspirin use, nonsteroidal anti-inflammatory use, and acetaminophen use