TABLE 2.

Summary of the effects of electrical stimulation on cell shortening and magnitude of [Ca²⁺]_i transients in PKD mutant-expressing cells

Maximal amplitude of cell shortening and of [Ca²⁺]_i transients were derived as described in the legend to Fig. 3 and “Experimental Procedures.” The results are reported as %RL for cell shortening and F/F₀ for [Ca²⁺]_i transients. The data are derived from experiments illustrated in Fig. 7 and presented as the means ± S.E. for control (n = 49), HA-caPKD (n = 49), Plum-caPKD (n = 54), and Plum-caPKD-S916A (n = 87), where n equals the number of cells analyzed.

	Control		HA-caPKD		Plum-caPKD		Plum-caPKD-S916A
	%RL	F/F0	%RL	F/F0	%RL	F/F0	%RL	F/F0
Initial	11.14 ± 0.47	1.75 ± 0.06	8.52 ± 0.51a,b	1.93 ± 0.07	9.81 ± 0.51	1.92 ± 0.06	11.14 ± 0.40	1.74 ± 0.04
Steady-state	4.97 ± 0.44	1.48 ± 0.04	3.04 ± 0.40c,d	1.59 ± 0.06	3.62 ± 0.38c,d	1.61 ± 0.05	5.04 ± 0.44	1.51 ± 0.04

^a Significantly different from initial control %RL values (p < 0.05).

^b Significantly different from initial Plum-caPKD-S916A %RL values (p < 0.05).

^c Significantly different from steady-state control %RL values (p < 0.05).

^d Significantly different from steady-state Plum-caPKD-S916A %RL values (p < 0.05).