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. 2010 Oct 15;285(53):42023–42032. doi: 10.1074/jbc.M110.145904

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — Q-PCR analysis of the mRNA levels of selected HIF target and ECM genes relative to 18S in controls (A) and TM1-deficient larvae compared with controls (MM) (B). A, mRNA levels of 3-dpf control larvae injected with MM morpholino are shown. The results are means ± S.D. (error bars) of three 30-larva pools. B, mRNA levels of 3-dpf TM1-injected larvae were compared with MM-injected controls. The results are shown as percentage of MM ± S.D. of three 30-larva pools. The dashed line indicates 100% of MM. *, p < 0.05; **, p < 0.01; ***, p < 0.001. Epo, erythropoietin; Vegf-a, vascular endothelial growth factor-a; Glut-1, glucose transporter-1; Ldha, lactate dehydrogenase-a; C-P4H-α(I), collagen prolyl 4-hydroxylase α(I) subunit; Col(IV)α3, the α3 chain of type IV collagen; Col(XVIII)α1, the α1 chain of type XVIII collagen.