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. 2010 Dec 17;10:37. doi: 10.1186/1471-2482-10-37

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Copyright ©2010 Armstrong et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Microscopy of oxidized regenerated cellulose-treated defects at 17 days post-surgery. Oxidized regenerated cellulose-treated adjacent 5 μm demineralized bone sections stained with H&E (upper) and Trichrome-EVG at ×2 (left) and ×10 magnification. The edge of the defect is identified with black/green arrows, and the area of magnification shown with a dotted box. Defects show partial healing with newly formed woven bone (light blue arrows) rich in cellular activity (osteoid shown with dark blue arrows). Early fibrotic tissue is observed within the defect (white stars). Blue stars indicate native collagen meshwork within the marrow and defect.