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. 2010 Oct-Dec;13(4):184–194. doi: 10.4103/0972-0707.73377

Table 4.

Summary of clinical studies on IRC.

Clinical study type Materials compared Parameters compared Comments
Four – six year follow up of resin inlay /onlay[85] (Leirskar et al. 2003) Tetric, Maxxim, Z 100 Form, MF, MD, CM, SR, SC 22% of restorations - acceptable and required minimal corrections.
2- surface restoration performed better than 3 surfaced and onlays
Seven year follow up resin inlay / onlay[86] (Donly et al. 1999) Cast gold, Concept F, CM, MD, SC, W, SR, (Ryge criteria) in molars and premolars 50-75% Alpha ratings for all parameters for concept. Concept yields clinically acceptable restorations particularly in premolars
One year follow up[87] (Cetin AR et al. 2009) AELITE, Filtek supreme XT, Tetricevoceram (Nano filled direct composites) Tescera ATL, estenia Class I and Class II SR, CM, MD, PS, GA, Rt (Ryge criteria) 85-100% Alpha ratings for all parameters for both direct and indirect composites.
Three year follow up[88] (Ducik w et al. 2010) Admira (ormocer), Grandio SR, F, MI, MD (Modified USPHS criteria) Alpha 1 score for overall success -71% - both materials Both materials have acceptable success after 36 months
Three yr follow up of CAD CAM composite and ceramic[89] (Vanoorbeek et al. 2010) marginal fit, periodontal parameters, volume loss, and wear patterns of the veneering material Survival rate andsuccess rate was 88 and 56% forcomposite
Survival rate andsuccess rate was 97 and 81% for ceramics
Increased wear and decreased esthetics of composite makes ceramics superior for CAD CAM restorations
One year results for direct and indirect composite inlays[90] (Mendonca et al. 2010) TetricEvo Ceram, Targis modified USPHS criteria forCM, MD, SC, AF, SR, MI, PS. This is a short term study.
CS, PS – no changes
CM, AF, SR similar to both materials.
Other parameters direct resin performed better.
A 4-6 yr retrospective study on cracked tooth bonded with indirect resin[91] (Signore et al. 2007) Direct composite restoration followed by indirect onlay Acceptable &survival rate-93 % 7% failure rate
A 3 yr RCT in evaluating direct and indirect composite for severely worn teeth[92] (Bartlett 2007) 32 direct and indirect restorations in premolar and molar of severely worn teeth. Wear fracture and loss of material was evaluated 22% fractured, 28% - complete loss of restoration. Direct and indirect resin composites for restoring worn posterior teeth is contraindicated.
10 year follow up on direct, indirect and ceramic inlay[93] (Thordruo 2006) Cerec Cos 2, Vita Dur, Brilliant DI, Estilux modified retrospective study on cracked tooth bonded with indirect resin (Signore et.al 2007California Dental Association Quality Evaluation System SR, F, SC 3 estilux inlays were replaced
6 vitadur inlays were repaired
Both materials were in acceptable range after 10 yrs.
5 yr follow up of direct inlays and conventional resin restorations[94] (Wassell et al. 2002) MD, MF, SR, W (USPHS criteria) More failure of inlays than conventional composites Direct inlay technique gave no clinical advantage over conventional, incremental placement
Composite resin fillings and inlays. An 11-year evaluation[95] (Pallesen et al. 2003). Brillinat DI, Estilux, SR isosit Class II restoration in molar and premolars (USPHS criteria) 70% of direct fillings and 88% of inlays were in acceptable ratings
Failure more in molar than premolar failure were fracture of restoration, secondary caries, fracture of tooth, loss of proximal contact, and loss of restoration
no significant difference between fillings and inlays or between types of restoration
Three year follow up of resin inlays[96] Manhart et al. 2010) Artglass, Charisma Class I, single and multisurface Class II inlays. (USPHS criteria) 89.8% of Artglass and 84.1% of Charisma inlays – acceptable
No significant differences between premolar and molars
Small inlays survived better
Failure was mainly due to bulk fracture, loss of marginal integrity.
Two year wear assessment[97] (Stober et al. 2008) Artglass Influence of gender, arch, and crown location on the occlusal wear In 1 yr – 19µ for anterior and premolar, 21µ for molars
In 2 yr – 36 µ for anterior, 44µ for premolar and 84µ
In 2 yr – 36 µ for anterior, 44µ for premolar and 84µ for molars.
Adhesively luted metal free crowns for5 years[98] (Lehmann et al. 2009) Artglass Artglass Location and preparation design on survival rates. 68 posterior, 46 anterior crowns with 0.5mm shoulder / 0.5mm chamfer was prepared 13 crowns – replaced, 5 crowns – repaired. No difference between location or preparation design on complications.
survival rate -96% in 3 yrs 88.5% in 5 yrs can be used as long term temporary crown increased plaque accumulation restricts the indication

MD- marginal discoloration, SC – secondary caries, SR- surface roughness, MF- marginal fit, W-wear, CM- color match, F- form, MI-marginal integrity.