Figure 6.

High-turnover mRNAs are recalcitrant to repression, regardless of their steady-state levels. The color code indicates, for each individual siRNA, whether the achieved silencing was >90%. Multiple siRNAs targeting the same transcript are plotted in groups close to each other. siRNAs were divided into bins based on abundance and turnover rate, and the pie charts indicate the fraction of siRNA that reached 90% silencing or better in each bin. Source data is available for this figure at www.nature.com/msb.

Source data for figure 4B,C and Figure 6 ^{(54.5KB, txt)}