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. 2010 Aug 4;39(1):110–121. doi: 10.1007/s10439-010-0131-2

Table 3.

The differences between the new results using the in vitro ATT data minus 3 mm and the in vitro ATT data plus 3 mm as inputs and the results using the original in vitro data as inputs during tuning of the knee-ligament parameters

Subject Inputs of in vitro ATT data Percentage change (%) ATT ACL force MCL force
Stiffness Zero load length R 2 RMS error (mm) R 2 RMS error (N) R 2 RMS error (N)
Healthy Plus 3 mm 1.85 (4.00) −0.15 (1.67) 0.628 1.10 0.863 212.8 0.852 191.6
Minus 3 mm −1.59 (6.69) −1.26 (7.17) 0.888 0.48 0.973 78.8 0.933 201.8
ACL-deficient Plus 3 mm 2.80 (6.38) −1.32 (2.60) 0.970 2.36 0.800 150.1
Minus 3 mm −2.71 (3.53) 0.16 (1.94) 0.966 0.59 0.746 54.2

Average percentage change of the calculated stiffness and zero load length of the ligament bundles were reported with standard deviations in parentheses to show the influence of different ATT inputs on the tuned ligament parameters. Coefficient of determination (R 2) and RMS error between the new results of ATT, ACL force, and MCL force during stance phase and the original results were reported to show the influence of different tuned knee–ligament parameters on the knee biomechanics. In this sensitivity study we chose to use the knee joint model with 4° of tibial slope as an example