Table 2.

Rank Order of Compounds in the Nitrite, NF-κB, QR1, and QR2 Assays

Nitrite		NF-κB		QR1		QR2
Compb	IC50 (μM)	Compb	IC50 (μM)	Compb	CD	Compb	IC50 (μM)
8	4.2	43	1.4	46	0.0047	16	0.16
47	5.9	53	1.9	41	0.012	9	0.19
46	7.2	46	2.1	42	1.8	34	0.32
34	7.2	41	2.5	44	1.8	29	0.45
17	17.4	47	2.5	11	4.3	44	0.48
14	26.5	17	4.7	47	4.4	17	1.4
15	28.4	12	5.2	40	9.4	53	2.9
12	31.5	15	5.4	38	11.3	30	3.3
16	33.7	39	6.6	49	16.6	46	3.5
43	34.5	28	9.2	28	23	43	4.1
53	45.6	34	13.1	8	27	40	4.8
38	47.0	42	17.0	9	29.4	39	10.5

^aThe compounds listed are the twelve most active compounds in each of the four assays out of thirty-two compounds tested.

^bThe compound numbers that are bolded appear in both the nitrile and NFκB columns.