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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Wound Repair Regen. 2010 Oct 13;18(6):586–593. doi: 10.1111/j.1524-475X.2010.00632.x

Figure 2. Effect of CpG ODN treatment on wound healing.

Figure 2

Six mm excisional biopsies were taken from the right and left dorsum of individual mice. One biopsy site (selected at random) was treated on days 0, 2 and 4 with BME alone while the other was treated with BME formulated with 50 μg of either CpG or control ODN. Serial photographs of representative biopsy sites from (A) normal BALB/c and (C) congenic TLR9 KO mice are shown. B, D) The mean rate of repair was calculated based on the original wound area of each biopsy site. The percent repair over time (mean ± SE of all sites, N = 6/treatment group from 2 independent experiments) is shown.

**; p < 0.001 for integrated area under the curve of BME + CpG ODN vs BME alone.