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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: HIV Med. 2011 Feb 1;12(2):97–108. doi: 10.1111/j.1468-1293.2010.00856.x

Table 2.

Epidemiologic Data Used in Decision Model

Epidemiologic Data Base Case Range Source
Pregnancies (per 100 person-years) in
HIV-infected women		 7.40 1.40-18.10* 38, 43
Pregnancy outcomes among HIV-infected women
 Live births per pregnancy 36.00% 27.00-45.00% 38
Probability of teratogenic events among HIV-infected women
 Prevalence of teratogenic events,
  no efavirenz exposure† 		2.72% 95% CI: 2.68-2.76% 39, 42
 Prevalence of teratogenic events
  with efavirenz exposure		 2.90% 95% CI: 1.60-4.90% 39
*

The range for this sensitivity analysis was derived using age-stratified pregnancy rates.43

†

The confidence intervals reported around the general population rate of teratogenic events from the Metropolitan Atlanta Congenital Defects Program (MACDP) used for the prevalence of teratogenic events with no efavirenz exposure were calculated by the Antiretroviral Pregnancy Registry.39 MACDP does not publish confidence intervals because population-based surveillance does not involve sampling.