. Author manuscript; available in PMC: 2012 Jan 1.

Published in final edited form as: Bioorg Med Chem Lett. 2010 Nov 5;21(1):338–341. doi: 10.1016/j.bmcl.2010.11.004

Table 2.

Inhibition of RMGPa by synthesized PT compounds

Compound	IC₅₀^a (μM) ±SD	Compound	IC₅₀^a (μM) ±SD
3	41.5±3.2	10	NI^b
5	0.21±0.1	11	53.8±4.9
6	2.87±0.1	12	46.4±3.6
8	20.1±1.1	1	194.1±17.5
9	15.2±0.7	Caffeine^c	75.3±6.6

Values are means of three experiments.

NI = no inhibition.

Caffeine was used as a positive control.