Table 3.
Compound | IC50a(μM)±SD for cancer cell lines |
||||
---|---|---|---|---|---|
PC3 | A549 | MCF-7 | HeLa | BGC-823 | |
5 | 6.75±0.57 | 136.1±10.1 | 559.6±45.5 | N/Ab | N/Ab |
6 | 5.32±0.43 | 996.5±80.7 | 373.6±23.7 | 17.1±0.9 | 9.54±0.78 |
8 | NAb | 770.1±65.6 | 397.5±15.8 | NAb | 19.3±1.66 |
9 | NAb | 892.5±46.8 | 565.3±22.4 | NAb | NAb |
10 | 66.3±5.56 | 62.9±5.69 | 603.5±44.5 | 63.1±2.8 | 25.9±1.49 |
11 | 8.51±0.73 | 194.2±10.6 | 32.5±2.79 | 105.4±11.2 | 12.7±0.85 |
12 | 10.8±0.08 | 0.89±0.07 | 0.33±0.04 | 56.7±4.9 | 7.64±0.19 |
1 | 19.7±1.55 | 16.8±2.13 | 87.2±8.46 | 19.1±2.1 | 2.41±0.22 |
Adriamycinc | 0.68±0.07 | 0.54±0.04 | 1.65±0.11 | 1.35±0.08 | 1.33±0.09 |
Values are means of three experiments.
NA = no activity.
Adriamycin was used as a positive control.