. Author manuscript; available in PMC: 2012 Jan 2.

Published in final edited form as: DNA Repair (Amst). 2010 Sep 15;10(1):111–116. doi: 10.1016/j.dnarep.2010.08.005

Table 2.

Main effects of 10 SNPs on melanoma risk in the additive model with P value ≤ 0.01

Gene	SNP	Wildtype	Heterozygote	Homozygous variant	OR (95%CI)^a	P-trend

		case/control	case/control	case/control
*ATR*	rs13091637	115/150	80/58	15/1	2.20 (1.53–3.16)	0.00002
*PARP1*	rs3219125	169/189	43/16	1/0	3.13 (1.75–5.74)	0.0002
*FANCA*	rs9926296	45/66	108/100	63/39	1.51 (1.15–1.99)	0.003
*BLM*	rs8037430	117/88	80/94	14/29	0.64 (0.48–0.87)	0.004
*MLH1*	rs1540354	132/154	68/49	11/4	1.69 (1.16–2.47)	0.006
*FANCA*	rs2239360	92/117	94/77	26/16	1.48 (1.11–1.98)	0.007
*BLM*	rs7175811	100/75	94/106	16/31	0.67 (0.50–0.90)	0.008
*PMS2*	rs3779109	132/156	71/53	9/4	1.66 (1.13–2.43)	0.009
*XRCC4*	rs35268	162/141	47/63	4/10	0.59 (0.40–0.88)	0.009
*XPG*	rs4150355	67/89	113/105	32/19	1.48 (1.10–2.00)	0.01

Adjusted by age.