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Dose schedules of bortezomib used in Leonard et al. (2005).
| Level | Dose and schedule within cycle |
|---|---|
| 1 | 0.7 mg/m2 on day 1 of each cycle |
| 2 | 0.7 mg/m2 on days 1 and 8 of each cycle |
| 3 | 0.7 mg/m2 on days 1 and 4 of each cycle |
| 4 | 1.0 mg/m2 on days 1 and 4 of each cycle |
| 5 | 1.3 mg/m2 on days 1 and 4 of each cycle |
