Table 1.

Chromosomal neo gene correction rates

Cell line	Vector	MOIa	Fraction G418R
HSNO39	none	-	<5.3 × 10−5
"	"	-	< 4.3 × 10−5
"	"	-	< 4.3 × 10−5
"	"	-	< 1.4 × 10−5
HSNO39	AAV-SNO648	40,000	9.6 × 10−4
"	"	40,000	6.7 × 10−5
"	"	400,000	2.0 × 10−3
"	"	400,000	1.4 × 10−3
HeLa	AAV-SNO648	40,000	<6.0 × 10−5
"	"	40,000	< 5.7 × 10−5
"	"	400,000	< 6.8 × 10−5
"	"	400,000	< 6.6 × 10−5
HSNO39	AAV-SNO39	375,000	< 6.3 × 10−5
"	"	1,500,000	<6.6 × 10−5
HSNO39	AAV-SNori	40,000	7.3 × 10−3
"	"	40,000	7.9 × 10−3
"	"	400,000	1.7 × 10−2
"	"	400,000	2.7 × 10−2
HeLa	AAV-SNori	100,000	7.3 × 10−3
"	"	100,000	5.3 × 10−3

^avector genomes per cell.