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. Author manuscript; available in PMC: 2012 Jan 13.
Published in final edited form as: Neuroscience. 2010 Oct 23;172:474–482. doi: 10.1016/j.neuroscience.2010.10.045

Figure 5. Comparison of motor coordination and basal nociceptive responses between Cre− and Cre+ Prph-fNR1 mice.

Figure 5

A: Rotorod test of gross motor coordination. Values are the latencies for the mice to fall off a slowly accelerating rod. B: Thermal tail withdrawal test. Times are the latency to withdrawal the tail from a 48.5 ºC hot water bath. C: Hot plate test. Values are the latency to lick the hind paw or jump after the mice were placed on a 52.5°C hot plate. D: Tail pressure test. Measurements were made with a Ugo Basile Analgesia-Meter at 3 points along the tail and averaged. Values are the pressure, in grams, at which the mouse twitched or withdrew its tail. E: Mechanical paw withdrawal test. Paw withdrawal thresholds to application of a graded series of von Frey fibers were estimated using the up-down method. Values are in grams of applied force. For A–E, n=10–17 mice of each genotype.