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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Bone. 2010 Aug 22;49(1):122–127. doi: 10.1016/j.bone.2010.08.011

Figure 1. IG9402 does not decrease bone turnover in mice.

Figure 1

Mice were treated with daily injections of alendronate or IG9402, starting 3 days prior to pellet implantation. Ten days after pellet implantation, mice were sacrificed and plasma and lumbar vertebrae were collected. Levels of circulating C-telopeptide (A), circulating osteocalcin (B) and mRNA for osteoclastic (C) and osteoblastic (D) genes were determined as indicated in Methods. Aln: alendronate. *: p<0.05 versus saline-placebo and #: p<0.05 versus saline-GC by two-way anova, n= 6–11 mice/group.