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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2010 Oct 16;123(1-2):30–36. doi: 10.1016/j.jsbmb.2010.10.002

Table 3.

Association between VDR expression and OS in Cox proportional hazards model

Overall, N=73 Early stage NSCLC, n=48 Late stage NSCLC, n=25
VDR expression Unadjusted HR
(95% CI)		 Adjusted HR
(95% CI) a 		Unadjusted HR
(95% CI)		 Adjusted HR
(95% CI)b 		Unadjusted HR
(95% CI)		 Adjusted HR
(95% CI) b
Nuclear VDR
 Low 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 High 0.52
(0.25-1.09)		 0.36
(0.17-0.79)		 0.59
(0.22-1.57)		 0.34
(0.11-1.09)		 0.39
(0.13-1.19)		 0.39
(0.11-1.34)
 P 0.085 0.011 0.29 0.069 0.098 0.135
Cytoplasmic VDR
 Low 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 High 0.99
(0.54-1.81)		 1.28
(0.65-2.49)		 1.23
(0.55-2.76)		 1.45
(0.58-3.62)		 0.93
(0.35-2.49)		 1.64
(0.49-5.47)
 P 0.963 0.478 0.621 0.433 0.885 0.418

VDR: Vitamin D receptor; OS: Overall survival; NSCLC: Non-small cell carcinoma

a

Adjusted for stage, age, histology, sex, smoking status

b

Adjusted for age, histology, sex, smoking status