. Author manuscript; available in PMC: 2012 May 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2010 Aug 21;80(1):265–272. doi: 10.1016/j.ijrobp.2010.05.023

Table 1.

Target and normal tissue planning criteria, for 6 fractions.

Region of interest	Dose criteria	Limit^*	Limit if the PTV overlaps non-liver normal tissues
GTV	Min to 0.5 cm³	95% of prescription	n/a
PTV_GTV^†	Min (max) to 0.5 cm³ volume	95% (140%) of prescription	80% of prescription
PTV_CTV^†	Min to 0.5 cm³	27.0 Gy	n/a
Large Bowel	Max to 0.5 cm³	28.2 Gy	30.0 Gy
Small Bowel	Max to 0.5 cm³	28.2 – 33.6 Gy	30.0 – 36.0 Gy
Stomach	Max to 0.5 cm³	28.2 – 30.0 Gy	30.0 – 33.6 Gy
Duodenum, esophagus	Max to 0.5 cm³	28.2 Gy	30.0 Gy
Kidney(s)	Mean to one or combined kidneys	10 Gy	n/a

Abbreviations: GTV = gross tumor volume; CTV = clinical target volume (GTV plus 0.8 cm expansion in liver); PTV = planning target volume (patient specific internal margin for breathing plus 0.3 cm setup margin expansion); PTV_GTV = PTV applied around the GTV; PTV_CTV = PTV applied around the CTV.

Notes:

Ranges indicate criteria was modified during the course of the trial

^†

For each patient the same PTV expansion was applied to each the GTV and CTV though dose criteria was different.