Table 1.
Summary description of all AN subjects.
| AN# | Age | Ear tested |
ABR | Pure tone thresholds (dB HL) | Speech (%) |
Gap detection (ms) |
Other clinical | Site of lesion | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 250 | 500 | 1000 | 2000 | 4000 | 6000 | |||||||||
| S1 | 30 | 23 | R | 7.0 | 15 | 15 | 0 | 5 | −5 | 5 | 98 | 6 | OTOF | Pre-synaptic |
| S2 | 32 | 17 | L | 7.4 | 30 | 30 | 20 | 25 | 15 | 25 | 100 | 12 | OTOF | Pre-synaptic |
| S3 | 33 | 13 | L | 7.9 | 25 | 15 | 10 | 10 | 0 | 20 | 88 | 11 | OTOF | Pre-synaptic |
| S4* | 38 | 19 | L | NR | 65 | 70 | 25 | 25 | 30 | 35 | 10 | 10 | Optic NP | Post-synaptic |
| S5 | 36 | 55 | R | NR | 60 | 60 | 20 | 25 | 25 | 35 | 36 | 10 | Vestibular NP | Post-synaptic |
| S6 | 40 | 13 | R | NR | 70 | 70 | 45 | 35 | 35 | 35 | 18 | 11 | Optic NP | Post-synaptic |
| S7* | 13 | 35 | L | NR | 60 | 80 | 40 | 25 | 10 | 10 | 50 | 11 | Peripheral NP | Post-synaptic |
| S8 | 10 | 28 | L | NR | 65 | 60 | 30 | 20 | 10 | 5 | 70 | 5 | undefined | |
| S9 | 7 | 37 | R | NR | 65 | 65 | 50 | 10 | 30 | 25 | 64 | 8 | undefined | |
| S10 | 27 | 19 | L | NR | 10 | 15 | 20 | 80 | 80 | 90 | 80 | 14 | undefined | |
| mean | 47 | 48 | 26 | 26 | 23 | 29 | 61 | 10 | ||||||
*
=cochlear implant (non-test ear); OTOF= hetereozygous otoferlin mutation; NP=neuropathy. NR=no response. The second column refers to AN subject numbers that were used in previously published manuscripts by our group (see Michalewski et al., 2009).